Hendrik Buikema Selected Research

NWT-03

1/2012

Attenuation of renovascular damage in Zucker diabetic fatty rat by NWT-03, an egg protein hydrolysate with ACE- and DPP4-inhibitory Activity.

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Hendrik Buikema Research Topics

Disease

9	Proteinuria 01/2016 - 12/2005
8	Myocardial Infarction 01/2009 - 03/2001
7	Cardiovascular Diseases (Cardiovascular Disease) 11/2013 - 12/2002
6	Heart Failure 06/2013 - 03/2003
5	Hypertension (High Blood Pressure) 06/2013 - 04/2003
3	Chronic Renal Insufficiency 01/2023 - 06/2013
3	Type 2 Diabetes Mellitus (MODY) 01/2017 - 01/2012
3	Inflammation (Inflammations) 01/2014 - 01/2009
3	Coronary Artery Disease (Coronary Atherosclerosis) 09/2006 - 11/2005
3	Left Ventricular Dysfunction 12/2005 - 03/2004
2	Pre-Eclampsia (Preeclampsia) 01/2013 - 01/2013
2	Albuminuria 01/2012 - 07/2002
2	Nephrosis 04/2009 - 06/2008
2	Essential Hypertension 11/2006 - 02/2003
2	Ischemia 03/2006 - 09/2004
2	Infarction (Infarctions) 03/2004 - 03/2003
1	Hypercholesterolemia 12/2023
1	Atherosclerosis 12/2023
1	Sclerosis 01/2014
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2014
1	Lymphopenia (Lymphocytopenia) 01/2014
1	Diabetic Nephropathies (Diabetic Nephropathy) 11/2013
1	Hypertrophy 06/2013
1	Fibrosis (Cirrhosis) 03/2013
1	Eclampsia 01/2013
1	Chronic Kidney Failure (Chronic Renal Failure) 09/2011
1	Hemorrhagic Shock 09/2009
1	Shock 09/2009
1	Cicatrix (Scar) 04/2009
1	Nephrotic Syndrome (Syndrome, Nephrotic) 06/2008
1	Thrombosis (Thrombus) 02/2008
1	Neointima 02/2008
1	Renal Insufficiency (Renal Failure) 11/2006

Drug/Important Bio-Agent (IBA)

7	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2009 - 03/2004
5	Angiotensin IIIBA 07/2015 - 12/2002
5	endothelium-dependent hyperpolarization factor (EDHF)IBA 02/2009 - 03/2003
4	Lisinopril (Prinivil)FDA LinkGeneric 01/2016 - 12/2005
4	salicylhydroxamic acid (SHAM)IBA 01/2014 - 03/2003
3	CholesterolIBA 12/2023 - 04/2009
3	Biomarkers (Surrogate Marker)IBA 01/2017 - 03/2013
3	Growth Differentiation Factor 15IBA 01/2017 - 03/2013
3	Proteins (Proteins, Gene)FDA Link 01/2014 - 04/2009
3	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 01/2009 - 12/2005
3	zofenoprilIBA 09/2006 - 03/2004
3	Quinapril (Accupril)FDA LinkGeneric 12/2005 - 09/2004
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016 - 03/2003
2	Messenger RNA (mRNA)IBA 01/2014 - 01/2012
2	CreatinineIBA 11/2013 - 06/2013
2	ErbB Receptors (EGF Receptor)IBA 06/2013 - 03/2009
2	AngiotensinsIBA 01/2013 - 02/2003
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2009 - 01/2009
2	CaveolinsIBA 04/2009 - 05/2008
2	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2009 - 06/2008
2	LipidsIBA 01/2009 - 11/2005
2	SodiumIBA 12/2005 - 02/2003
1	Apolipoproteins E (ApoE)IBA 12/2023
1	ApolipoproteinsIBA 12/2023
1	Bile Acids and Salts (Bile Acids)IBA 12/2023
1	NitratesIBA 01/2023
1	NitritesIBA 01/2023
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2023
1	Trinitrotoluene (TNT)IBA 01/2017
1	pro-brain natriuretic peptide (1-76)IBA 01/2017
1	VildagliptinIBA 01/2014
1	Glucose (Dextrose)FDA LinkGeneric 01/2014
1	Blood Glucose (Blood Sugar)IBA 01/2014
1	SEW2871IBA 01/2014
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2014
1	Phenol (Carbolic Acid)FDA Link 06/2013
1	PKI 166IBA 06/2013
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 06/2013
1	Streptozocin (Streptozotocin)FDA Link 03/2013
1	EndotoxinsIBA 01/2013
1	LipopolysaccharidesIBA 01/2013
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 01/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2012
1	Egg ProteinsIBA 01/2012
1	NWT-03IBA 01/2012
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2011
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 09/2009
1	Nitrous Oxide (Laughing Gas)IBA 09/2009
1	Isoflurane FDA LinkGeneric 09/2009
1	Anesthetics (Anesthetic Agents)IBA 09/2009
1	Transforming Growth Factor beta (TGF-beta)IBA 04/2009
1	Insulin (Novolin)FDA Link 04/2009
1	AlbuminsIBA 04/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2009
1	Growth Factor ReceptorsIBA 04/2009
1	oxidized low density lipoproteinIBA 04/2009
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 02/2009
1	CollagenIBA 01/2009
1	Rosuvastatin Calcium (Crestor)FDA Link 02/2008

Therapy/Procedure

6	Therapeutics 04/2009 - 03/2004
3	Ligation 12/2005 - 03/2001
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2014 - 03/2013
1	Nephrectomy 01/2016
1	Blood Transfusion (Blood Transfusions) 03/2013
1	Anesthesia 09/2009
1	Drug-Eluting Stents 02/2008
1	Stents 02/2008